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What is ALUNBRIG® (brigatinib)?

ALUNBRIG is a once-daily oral prescription medication that helps treat adults with ALK+ metastatic NSCLC.

Who Can Be Treated With ALUNBRIG?

ALUNBRIG is approved to treat adults with NSCLC:

  • that has an abnormal ALK gene, and
  • that has spread to other parts of the body

It is not known if ALUNBRIG is safe and effective in children.

How Does ALUNBRIG Work?

ALUNBRIG is a type of targeted therapy. Targeted therapies can inhibit or slow the disease growth, progression, and spread of cancer by targeting specific molecules that are responsible for cancer cell growth.

  • ALUNBRIG is a tyrosine kinase inhibitor, or ALK inhibitor
  • ALUNBRIG works by blocking the abnormal ALK protein responsible for growth and spread of ALK+ NSCLC
Learn About ALUNBRIG When You Are Newly Diagnosed Learn About ALUNBRIG After Treatment With Crizotinib

Glossary

ALK gene-A gene that makes a protein called anaplastic lymphoma kinase or ALK, which is involved in cell growth. Mutated or genetically changed forms of the ALK gene and protein have been found in some types of cancer, such as NSCLC.

Targeted therapy-A type of treatment that can inhibit or slow the disease growth, progression, and spread of cancer by targeting specific molecules that are responsible for cancer cell growth. Some targeted therapies block the action of certain enzymes, proteins, or other molecules involved in the growth and spread of cancer cells.

A gene that makes a protein called anaplastic lymphoma kinase or ALK, which is involved in cell growth. Mutated or genetically changed forms of the ALK gene and protein have been found in some types of cancer, such as NSCLC.

A type of treatment that can inhibit or slow the disease growth, progression, and spread of cancer by targeting specific molecules that are responsible for cancer cell growth. Some targeted therapies block the action of certain enzymes, proteins, or other molecules involved in the growth and spread of cancer cells.


 

 

 

ALUNBRIG(TM) BRIGATINIB 39 mg TABLETS

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ALUNBRIG(TM) BRIGATINIB 39 mg TABLETS

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In Vitro: ALUNBRIG Inhibited 17
ALK-Inhibitor-Resistant Mutations1,2

ALUNBRIG exhibited in vivo antitumor activity against 4 mutant forms of EML4-ALK, including the G1202R and L1196M mutants identified in NSCLC tumors in patients who had progressed on crizotinib.


 

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